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Biomarker Discovery Development of Novel Tools

Studying the Pathophysiology and Functional Circuitry of neurological diseases plays a critical role in shaping Electrode Technology, where advances in Electrode Design can reveal new dimensions of neural activity, enabling more precise targeting and improved therapeutic outcomes. Leveraging Perioperative Electrophysiology (e.g., EEG, EMG, peripheral field potentials [PF], local field potentials [LFP], and single-unit activity [SUA]), along with Signal Processing, Machine Learning Decoding, Wearable Sensors, and Neuromodulation Techniques (e.g., SCS and DBS), our research focuses on developing a suite of innovative tools. These include High-Resolution Functional Brain and Spinal Mapping, Electrophysiology-Guided Target Localization, improved Electrode Placement, Clinical Programming Guided by Real-Time Neural Data, Robust and Rapid Data Visualization Platforms, and Diagnostic and Prognostic Tools. We are also working to Integrate Smart Health Wearables into clinical decision-making frameworks and Optimize Neuromodulation Therapy to enhance patient-specific outcomes.